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Table 4 Univariate and multivariate analysis of survival: prognostic factors of survival after SRS

From: The prognostic value of tumor necrosis in patients undergoing stereotactic radiosurgery of brain metastases

Factor

Univariate

Multivariate

 

p-value

p-value

Age

0.004

0.05

KPS

0.0001

0.001

RPA class

0.001

0.05

WBI

0.04

0.05

Tumor necrosis

0.05

0.001

Localization of lesion

0.007

0.002

Number of brain metastasis

0.02

0.09

Dose

0.002

0.64

Gender

0.46

 

Improvement of symptoms

0.45

 

Status of primary lesion (active/ controlled)

0.14

 

Tumor size

0.47

 

Numbers of extracranial metastases

0.43

 

Chemotherapy

0.42

 

Operation

0.23

 

Radiation

0.54

 
  1. Abbreviations:
  2. KPS Karnofsky performance status, RPA Recursive partitioning analysis, WBI Whole brain irradiation.