Fig. 3

HE staining of rat 7 (MRI based RT group, 32 days post inoculation) confirms the presence of GB. On the overview picture (left) central tumor necrosis (a), tumor (b), infiltration (c) of the surrounding healthy brain tissue (d) can be seen. The detailed section shows increased cellularity, more nuclear pleomorphism and atypia, increased proliferation (e), microvascular hyperplasia (f) and necrosis (g)