Fig. 3

Schematic representation of the two reported kinds of TNT connection to the cell body. On the left side a close-ended TNT is illustrated. Instead of membrane continuity there is a distinct junction between the connected cells recognizable. Such a junction is mostly found at one end of the nanotube as drawn here, but it has been also observed that these junctions can dynamically shift along the membrane tunnel. On the right side an open-ended nanotube is drawn, there the membrane of the tunnel has been fused with the plasma membrane of the connected cell and thus a membrane continuity was generated