Fig. 2

a Dendrogram (the “distance” indicates the closeness of either individual data points or clusters and the “sample index” is the number of data); b clustering classes based on the opinion of the radiologist and oncologist in which PTV3 correlates with ADC < 0.8 mm2/s and Ktrans > 3; PTV2 with 0.65 < ADC ≤ 1 mm2/s and 1 < Ktrans ≤ 3; and finally PTV1 with 1 < ADC mm2/s and Ktrans < 1