Table 4 Multivariate analyses with respect to factors and the risk of HT
Variable | Multivariate analyses | |
|---|---|---|
HR (95% CI) | p value | |
The Dtmean model | ||
Age (per year increase) | 0.981 (0.968–0.993) | 0.002* |
Female (vs male) | 1.551 (1.121–2.146) | 0.008* |
Chemotherapy (vs no) | 1.192 (0.747–1.902) | 0.461 |
Thyrotoxicosis (vs no) | 0.673 (0.481–0.943) | 0.021* |
Thyroid volume (per cm3 increase) | 0.929 (0.899–0.960) | 0.000* |
Dtmean (per Gy increase) | 1.000 (1.000–1.001) | 0.001* |
The Vt 30 model | ||
Age (per year increase) | 0.981 (0.969–0.993) | 0.002* |
Female (vs male) | 1.562 (1.130–2.519) | 0.007* |
Chemotherapy (vs no) | 1.196 (0.746–1.917) | 0.457 |
Thyrotoxicosis (vs no) | 0.672 (0.480–0.941) | 0.021* |
Thyroid volume (per cm3 increase) | 0.929 (0.899–0.960) | 0.000* |
Thyroid Vt30 (per % increase) | 6.613 (1.968–19.304) | 0.002* |
The Vt 40 model | ||
Age (per year increase) | 0.981 (0.969–0.994) | 0.003* |
Female (vs male) | 1.550 (1.121–2.143) | 0.008* |
Chemotherapy (vs no) | 1.246 (0.780–1.992) | 0.357 |
Thyrotoxicosis (vs no) | 0.684 (0.424–1.092) | 0.027* |
Thyroid volume (per cm3 increase) | 0.931 (0.901–1.963) | 0.000* |
Thyroid Vt40 (per % increase) | 4.411 (1.732–11.233) | 0.002* |
The Vt 50 Model | ||
Age (per year increase) | 0.981 (0.968–0.993) | 0.002* |
Female (vs male) | 1.568 (1.134–2.169) | 0.006* |
Chemotherapy (vs no) | 1.332 (0.841–2.112) | 0.222 |
Thyrotoxicosis (vs no) | 0.686 (0.490–0.960) | 0.028* |
Thyroid volume (per cm3 increase) | 0.930 (0.900–0.961) | 0.000* |
Thyroid Vt50 (per % increase) | 4.689 (1.747–12.591) | 0.002* |
The Vt 45 Model | ||
Age (per year increase) | 0.981 (0.969–0.993) | 0.003* |
Female (vs male) | 1.559 (1.127–2.155) | 0.007* |
Chemotherapy (vs no) | 1.294 (0.813–2.060) | 0.277 |
Thyrotoxicosis (vs no) | 0.688 (0.492–0.964) | 0.030* |
Thyroid volume (per cm3 increase) | 0.932 (0.902–0.964) | 0.000* |
Thyroid Vt45 (per % increase) | 4.158 (1.639–10.547) | 0.003* |