Table 3 Basic demographic characteristics and radiosurgical treatment parameters according to the occurrence of early-onset adverse radiation effects

Patients

16

30

Median age at GKRS, years

49 (21–76)

48 (11–83)

0.533^a

Sex (%)

0.210^b

 Male

4 (29.4)

14 (46.7)

 Female

12 (70.6)

16 (53.3)

Laterality (%)

0.347^b

 Left

7 (43.8)

20 (66.7)

 Right

9 (56.2)

10 (33.3)

Tumour component (%)

0.694^b

 Solid

14 (87.5)

24 (80.0)

 Cystic

2 (12.5)

6 (20.0)

Brainstem contact (%)

11 (68.8)

18 (60.0)

0.750^b

Prior microsurgery (%)

5 (31.3)

10 (33.3)

1.000^b

Transient expansion (%)

11 (68.8)

5 (16.7)

0.001^b

Tumour location ^c (%)

 A: Primary intracranial

2 (12.5)

14 (46.7)

0.026^b

 B: Jugular foramen with intracranial extension

1 (6.3)

2 (6.7)

1.000^b

 C: Primary extracranial with foraminal extension

2 (12.5)

7 (23.3)

0.463^b

 D: Intra-/extracranial extension (dumb-bell shaped)

11 (68.8)

7 (23.3)

0.004^b

Median tumour volume, cm³

4.85 (2.4–10.8)

3.1 (0.2–12.3)

0.003^a

Median follow-up period, months

48.5 (24–136)

52 (9–123)

0.729^a

Median marginal dose, Gy

13.0 (12.0–14.0)

13.0 (12.0–14.0)

0.868^a

Median maximal dose, Gy

26.2 (24.4–28.7)

26.1 (24.0–28.7)

0.641^a