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Table 3 Chi square analysis for pre-RT and post-RT NLR

From: Association of neutrophil-to-lymphocyte ratio, radiotherapy fractionation/technique, and risk of development of distant metastasis among patients with locally advanced rectal cancer

 

Pre-RT NLR

Post-RT NLR

p value

< 4.0

≥ 4.0

p value

< 4.0

≥ 4.0

Sex

 Male

0.234

758 (90.9)

76 (9.1)

0.024

502 (57.0)

378 (43.0)

 Female

417 (92.3)

35 (7.7)

298 (62.7)

177 (37.3)

icT

 T1/2

0.557

107 (91.5)

10 (8.5)

0.024

88 (67.2)

43 (32.8)

 T3/4

1056 (91.3)

101 (8.7)

101 (57.9)

510 (42.1)

icN

 N0

0.453

211 (90.9)

21 (9.1)

0.307

155 (61.5)

97 (38.5)

 N1/2

915 (91.4)

86 (8.6)

605 (57.5)

444 (42.3)

RT modality

 3D-CRT

0.48

732 (91.3)

70 (8.7)

< 0.001

532 (62.5)

319 (37.5)

 Tomotherapy

443 (91.5)

41 (8.5)

268 (53.2)

236 (46.8)

ypT

 T1/2

0.004

599 (93.6)

42 (6.4)

< 0.001

427 (63.9)

241 (36.1)

 T3/4

573 (89.3)

69 (10.7)

371 (54.3)

312 (45.7)

ypN

 N0

0.386

855 (91.5)

79 (8.5)

0.15

574 (58.5)

407 (41.5)

 N1/2

318 (90.9)

32 (9.1)

224 (60.2)

148 (39.8)

Adjuvant chemotherapy

 No

0.389

539 (91.0)

53 (9.0)

0.001

343 (54.6)

285 (45.4)

 Yes

636 (91.6)

58 (8.4)

457 (62.9)

270 (37.1)

RT fractionation

 LCRT

0.513

1147 (91.3)

109 (8.7)

0.012

776 (58.6)

549 (41.4)

 SCRT

28 (93.3)

2 (6.7)

24 (80.0)

6 (20.0)

  1. 3D-CRT three-dimensional conformal radiotherapy, LCRT long-course RT, SCRT short-course RT