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Table 4 Comparison of normal tissue dose between our center and other center

From: A retrospective study of adjuvant proton radiotherapy for breast cancer after lumpectomy: a comparison of conventional-dose and hypofractionated dose

 

Our center

Sagar A. Patel (2017)

Mirjam E. MAST (2014)

Anna M. Flejimer (2015)

Carmen Ares (2010)

John J. Cuaron

IMPT

Photon

Proton

IMPT-BH

IMRT-BH

MRT-FB

MPT-FB

Photon with gating

Phton-fb

IMPT

3D-RT

IMRT

IMPT

Proton

Ipsilateral lungipsilateral lung

V5

30.72 ± 9.95%

  

7.1 ± 2.7%

21.4 ± 6.6%

21.9 ± 7.1%

7.7 ± 2.7%

   

27 ± 3%

46 ± 12%

17 ± 7%

4.35(22.5–53.8)

V10

23.38 ± 8.49%

      

21.5 ± 10.0%

23.3 ± 13.2%

21.1 ± 4.4%

    

V20

13.41 ± 5.91%

26.04 ± 4.30%

15.18 ± 3.66%

2.5 ± 1.4%

10.9 ± 4.7%

12.4 ± 5.7%

2.8 ± 1.4%

16.4 ± 8.1%

18.2 ± 10.9%

9.4 ± 1.8%

14 ± 3%

9 ± 1%

7 ± 4%

16.5(6.1–30.3)

Dmean

6.61 ± 2.52 Gy

13.30 ± 1.70 Gy

7.63 ± 1.27 Gy

1.5 ± 0.6 Gy

5.4 ± 1.8 Gy

6.1 ± 2.3 Gy

1.6 ± 0.6 Gy

9.0 ± 3.9 Gy

9.7 ± 5.1 Gy

5.5 ± 1.1 Gy

17 ± 2 Gy

15 ± 2 Gy

7 ± 3 Gy

 

Heart (left breast cancer)

D2%

15.40 ± 9.90 Gy

      

11.0 ± 12.1 Gy

25.4 ± 15.4 Gy

6.0 ± 3.8 Gy

    

V5

4.74 ± 2.87%

  

0.1 ± 0.2%

2.5 ± 2.1%

7.4 ± 4.7%

0.5 ± 0.8%

3.7 ± 3.7%

7.6 ± 4.2%

2.4 ± 1.6%

10 ± 7%

42 ± 9%

2 ± 2%

0.00(0.17–14.40)

V20

1.63 ± 0.85%

1.97 ± 4.40%

0.86 ± 0.68%

0

0.6 ± 0.8%

3.5 ± 3.0%

0.1 ± 0.2%

0.9 ± 1.5%

3.1 ± 2.4%

0.2 ± 0.3%

4 ± 4%

3 ± 2%

0 ± 1%

1.16(0–6.0)

Dmean

0.98 ± 0.63 Gy

2.09 ± 1.48 Gy

0.98 ± 0.66 Gy

0.1 ± 0 Gy

1.5 ± 0.5 Gy

2.7 ± 1.3 Gy

0.2 ± 0.1 Gy

1.6 ± 0.8 Gy

2.7 ± 1.2 Gy

0.4 ± 0.3 Gy

9 ± 4 Gy

12 ± 2 Gy

1 ± 1 Gy

1.0(0.09–3.20)

LAD (left anterior descending artery)

D2%

28.59 ± 11.05 Gy

      

21.9 ± 16.1 Gy

41.8 ± 8.4 Gy

12.8 ± 3.0 Gy

    

Dmean

4.86 ± 2.42 Gy

  

0.3 ± 0.2 Gy

6.7 ± 5.1 Gy

14.9 ± 9.3 Gy

0.7 ± 0.8 Gy

9.7 ± 9.6 Gy

22.0 ± 11.7 Gy

4.0 ± 0.9 Gy

    
  1. IMPT intensity-modulated proton therapy; BH breath hold; FB free breathing; IMRT intensity modulated radiation therapy