Fig. 1

Disruption of BBB homeostasis following WBRT in immunocompetent mice. A–D Significant increase in 14C-sucrose (A, B) and 3H-ivermectin (C, D) uptake observed regionally and in whole brains 12 h following WBRT (15.5 Gy) in wild-type C57Bl/6 mice (p < 0.05)