Fig. 3

Increased BBB permeability following WBRT in immunocompetent mice is time and size-dependent. A–D Significant increase in 14C-AIB (A) and 3 kDa TxRd (C) uptake observed 12 h following WBRT (15.5 Gy) in wild-type C57Bl/6 mice, but not in athymic nude C57Bl/6 mice (B, D) (p < 0.05)