Automatic IMRT treatment planning through fluence prediction and plan fine-tuning for nasopharyngeal carcinoma

Radiation Oncology

Table 1 Optimization objectives were set according to prescription dose and predicted fluence generated dose information

ROI name	Objective type	Objective dose (Gy)	Priority
PTV-GTV	Maximum D_0%	73.5	70
PTV-GTV	Minimum D_100%	71.5	150
PTV-1-Crop	Maximum D_0%	PTV-1’ Px-dose + 3	70
PTV-1	Minimum D_100%	PTV-1’ Px-dose	150
PTV-2-Crop	Maximum D_0%	PTV-2’ Px-dose + 6	70
PTV-2	Minimum D_100%	PTV-2’ Px-dose	150
PTV-LN(L)	Maximum D_0%	PTV-LN(L)’ Px-dose + 3	70
PTV-LN(L)	Minimum D_100%	PTV-LN(L)’ Px-dose + 1.5	150
PTV-LN(R)	Maximum D_0%	PTV-LN(R)’ Px-dose + 3	70
PTV-LN(R)	Minimum D_100%	PTV-LN(R)’ Px-dose + 1.5	150
Brainstem	Maximum gEUD, a = 20	Predicted gEUD × 0.85	50
Brainstem 3 mm	Maximum gEUD, a = 20	Predicted gEUD × 0.85	50
Spinal cord	Maximum gEUD, a = 20	Predicted gEUD × 0.85	50
Spinal cord 3 mm	Maximum gEUD, a = 20	Predicted gEUD × 0.85	50
Left normal parotid	Maximum gEUD, a = 3	Predicted gEUD × 0.75	50
Right normal parotid	Maximum gEUD, a = 3	Predicted gEUD × 0.75	50
Left optic nerve	Maximum gEUD, a = 1	Predicted gEUD	50
Right optic nerve	Maximum gEUD, a = 1	Predicted gEUD	50
Chiasm	Maximum gEUD, a = 1	Predicted gEUD	50
Ring 2 cm	Maximum D_1%	Predicted dose × 0.95	50
	Maximum D_20%	Predicted dose × 0.95	50
	Maximum D_50%	Predicted dose × 0.95	50
	Maximum gEUD, a = 15	Predicted gEUD × 0.95	50
40 Gy-PTV2	Maximum D_1%	Predicted dose × 0.95	50
	Maximum D_20%	Predicted dose × 0.95	50
	Maximum D_50%	Predicted dose × 0.95	50
	Maximum gEUD, a = 10	Predicted gEUD × 0.95	50

ISSN: 1748-717X