Skip to main content

Table 1 Guidelines of CTV delineation

From: Hypofractionated radiotherapy with simultaneous tumor bed boost (Hi-RISE) in breast cancer patients receiving upfront breast-conserving surgery: study protocol for a phase III randomized controlled trial

CTV

Cranial

Caudal

Medial

Lateral

Ventral

Dorsal

Breast

Upper border of palpable/visible breast tissue; up to the inferior edge of the sternoclavicular joint

Most caudal CT slice with visible breast/mammary fold

Medial border of palpable/visible breast tissue; maximally to the parasternal line

Lateral border of visible/palpable mammary gland

0.5 cm beneath skin surface (including visible breast tissue)

Anterior edge of the pectoralis major/intercostal muscles/ribs

Axillary level I

0.5 cm cranial to axillary vein

Level of 4th anterior rib, including postoperative change of SLNB

Axillary level II; chestwall

The line between pectoralis major and deltoid/ latissimus dorsi

Pectoralis major; pectoralis minor

Thoracodorsal vessels; the line between intercostal muscles and deltoid/ latissimus dorsi

Axillary level II

Cranial edge of axillary artery

Caudal edge of pectoralis minor

Medial border of pectoralis minor

Lateral border of pectoralis minor

Posterior surface of pectoralis minor

0.5 cm dorsal to axillary vein; anterior edge of the intercostal muscles

Axillary level III

0.5 cm cranial to subclavian vein

0.5 cm caudal to subclavian vein

Junction of subclavian and internal jugular veins

Medial border of the pectoralis minor

Pectoralis major

0.5 cm dorsal to axillary vein; anterior edge of the intercostal muscles

INT

0.5 cm cranial to subclavian vein

Caudal border of CTV axillary level II

Medial border of pectoralis minor

Lateral border of pectoralis minor

Pectoralis major

Pectoralis mimor

SCN

Caudal edge of cricoid cartilage

Junction of subclavian and internal jugular veins

Medial edge of the internal jugular vein, excluding thyroid and the common carotid artery

Sternocleidomastoid; the junction of clavicle and 1st rib

Medial edge of the sternocleidomastoid/clavicle

Ventral edge of the scalene muscle bundles

IMN

0.5 cm caudal to subclavian vein

Cranial edge of 4th rib

0.5 cm medial to the internal thoracic vessels

0.5 cm lateral to the internal thoracic vessels

Ventral edge of the internal thoracic vessels

Parietal pleura

  1. CTV: clinical target volume; INT: interpectoral lymph nodes; SCN: supraclavicular lymph nodes; IMN: internal mammary node; SLNB: sentinel lymph node biopsy