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Fig. 6 | Radiation Oncology

Fig. 6

From: Possible association of dose rate and the development of late visual toxicity for patients with intracranial tumours treated with pencil beam scanned proton therapy

Fig. 6

Overlay of dose and voxel wise maximum dose rate (MDR) distributions on CT images of the two toxicity cases (T4-03 and T3-06). Dose rate distributions are shown for the fields contributing the highest MDR values. The maximum dose rate distribution above 3 GyRBE/s threshold is shown. High dose rate areas overlap with pre-chiasmatic left optic nerve areas, which developed radiation induced optic neuropathy (RION) on the follow-up MR images. The optic chiasm is shown in yellow, left and right optic nerves are shown in red and blue, respectively, CTV is shown in green, and area of RION is indicated with a red arrow. The dose and dose-rate colourwashes are displayed at the centre of the Figure

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