Fig. 1

Representative axial CT scans showing inter-observer variability during delineation of the GTV in two patients. Patient 18 (A, B) represents the best JCI case (hypodense tumor with good concordance). Patient 7 (C, D) represents the worst JCI case (red arrow: iso-attenuating tumor with dilated bile duct; yellow arrow: normal pancreactic parenchyma) gsGTVs are shown in red; radiation oncologists’ GTVs are shown in blue and green at the arterial (A, C) and the venous phases (B, D)