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Table 4 Dose-volume reporting for organs at risk at each CT phase for the gold standard and the operators (n = 20 patients)

From: A comparison of target volumes drawn on arterial and venous phase scans during radiation therapy planning for patients with pancreatic cancer: the PANCRINJ study

 

Gold standard

  

Operators

  

P value gold standard vs. operators

Arterial

Venous

P value

Arterial

Venous

P value

Arterial

Venous

Dmax (Gy)

Duodenum

median (range)

54.3

(21.9–54.9)

54.3

(36.8–54.8)

0.71

54.4

(29.8–55.5)

54.3

(48-55.5)

0.79

0.085

0.1

 

≤ 55 Gy

20 (100%)

20 (100%)

 

18 (90%)

17 (85%)

   
 

> 55 Gy

0 (0%)

0 (0%)

 

2 (10%)

3 (15%)

   

Stomach

median (range)

51.9

(1-55.5)

51.6

(0.8–54.7)

0.6

50

(1.45-55)

50.3

(1.4–54.7)

0.45

0.03

0.07

 

≤ 55 Gy

19 (95%)

20 (100%)

 

18 (90%)

20 (100%)

   
 

> 55 Gy

1 (5%)

0 (0%)

 

2 (10%)

0 (0%)

   

Bowel

median (range)

39.4 (13.3–54.1)

40.4 (11.8–54.3)

0.33

45.8 (11.9–56)

43.5 (12.7–55.4)

1

0.07

0.02

 

≤ 55 Gy

20 (100%)

20 (100%)

 

19 (95%)

19 (95%)

   
 

> 55 Gy

0 (0%)

0 (0%)

 

1 (5%)

1 (5%)

   

V50 Gy (%)

Duodenum

median (range)

4.35

(0–22)

2.9

(0.3–10.9)

0.38

10 (0-29.5)

9.7 (0-31.2)

0.1

0.006

0.0003

 

≤ 10%

14 (70%)

14 (70%)

 

10 (50%)

10 (50%)

   
 

> 10%

6 (30%)

6 (30%)

 

10 (50%)

10 (50%)

   

Stomach

median (range)

0

(0-4.9)

0

(0-4.1)

0.26

0.1

(0-7.25)

0.1

(0–6)

0.96

0.04

0.04

 

≤ 10%

20 (100%)

20 (100%)

 

20 (100%)

20 (100%)

   
 

> 10%

0 (0%)

0 (0%)

 

0 (0%)

0 (0%)

   

Bowel

median

0

0

1

0

0

1

0.06

0.06

 

≤ 10%

20 (100%)

20 (100%)

 

20 (100%)

20 (100%)

   
 

> 10%

0 (0%)

0 (0%)

 

0 (0%)

0 (0%)

   

V50 Gy (cc)

Duodenum

median (range)

3.5

(0-24.7)

2.8

(0.3–10.4)

0.8

9 (0.5–31.5)

8.8 (0.5–17.3)

0.7

0.028

0.0008

 

≤ 10 cc

17 (70%)

15 (75%)

 

9 (45%)

8 (40%)

   
 

> 10 cc

6 (30%)

5 (25%)

 

11 (55%)

12 (60%)

   

Bowel

median (range)

0 (0-8.8)

0 (0-4.9)

0.8

0 (0–16)

0.02(0-10.2)

0.36

0.008

0.008

 

≤ 10 cc

20 (100%)

20 (100%)

 

19 (95%)

19 (95%)

   
 

> 10 cc

0 (0%)

0 (0%)

 

0 (5%)

1 (5%)

   

V45 Gy (%)

Duodenum

median (range)

6.7 (0.1–27.4)

4.15 (0.4–13.9)

0.21

11.28 (0-39.9)

11.8 (0-54.2)

0.16

0.005

< 0.0001

 

≤ 15%

15 (75%)

16 (80%)

 

10 (50%)

11 (55%)

   
 

> 15%

5 (25%)

4 (20%)

 

10 (50%)

9 (45%)

   

Stomach

median (range)

0.2 (0-6.8)

0 (0-5.6)

0.26

0.35 (0-9.9)

0.25 (0-7.9)

0.84

0.02

0.008

 

≤ 15%

20 (100%)

20 (100%)

 

20 (100%)

20 (100%)

   
 

> 15%

0 (0%)

0 (0%)

 

0 (0%)

0 (0%)

   

Bowel

median (range)

0 (0–2)

0 (0-1.3)

0.75

0 (0-3.3)

0 (0-2.3)

0.1

0.008

0.03

 

≤ 15%

20 (100%)

20 (100%)

 

20 (100%)

20 (100%)

   
 

> 15%

0 (0%)

0 (0%)

 

0 (0%)

0 (0%)

   

V45 Gy (cc)

         

Stomach

median (range)

0.45 (0-12.7)

0 (0-3.2)

0.12

1 (0-17.5)

0.78 (0-13.9)

0.83

0.06

0.002

 

≤ 75 cc

20 (100%)

20 (100%)

 

20 (100%)

20 (100%)

   
 

> 75 cc

0 (0%)

0 (0%)

 

0 (0%)

0 (0%)

   

V15 Gy (cc)

Bowel

median (range)

54.1 (0-181.7)

53.2 (0-252.6)

0.87

75.7 (0-336.3)

86.5 (0-361)

0.9

0.001

0.0001

 

≤ 120 cc

17 (85%)

17 (85%)

 

14 (70%)

14 (70%)

   
 

> 120 cc

3 (15%)

3 (15%)

 

6 (30%)

6 (30%)

   

Dmean(Gy)

Kidneys

median

(range)

4.4 (0.6–11.3)

4.1

(0.1–10.9)

0.71

5.1

(0.85–12.7)

6

(1.1–12.9)

0.07

0.006

< 0.001

 

≤ 18 Gy

20 (100%)

20 (100%)

 

20 (100%)

20 (100%)

   
 

> 18 Gy

0 (0%)

0 (0%)

 

0 (0%)

0 (0%)

   

Liver

median (range)

2.4 (1-8.5)

2.1 (1-8.5)

0.0006

3.4 (1.3–8.7)

3.4 (1.1–7.8)

0.11

0.0011

< 0.0001

 

≤ 25 GY

20 (100%)

20 (100%)

 

20 (100%)

20 (100%)

   
 

> 25 Gy

0 (0%)

0 (0%)

 

0 (0%)

0 (0%)

   

V20 (%)

Kidneys

median (range)

0 (0-10.9)

0.1 (0–11)

0.1

1 (0-7.7)

1 (0-10.5)

0.72

0.03

0.07

 

≤ 32%

20 (100%)

20 (100%)

 

20 (100%)

20 (100%)

   
 

> 32%

0 (0%)

0 (0%)

 

0 (0%)

0 (0%)

   

D0.1 cc (Gy)

         

Spinal cord

median

(range)

13.2

(6.9–22.1)

13.2

(3.9–24)

0.5

14.5

(5-22.9)

13.8

(6–23)

0.7

0.09

0.04

 

≤ 45 Gy

20 (100%)

20 (100%)

 

20 (100%)

20 (100%)

   
 

> 44 Gy

0 (0%)

0 (0%)

 

0 (0%)

0 (0%)