Quantitative PSMA-PET parameters in localized prostate cancer: prognostic and potential predictive value

Radiation Oncology

Table 2 Univariable Cox regression for all patients (intermediate and high-risk)

Parameter	HR	95% CI	p value	HR	95% CI	p value
	BCR			OS
Age > 74 y	0.29	0.09–1	0.049	5.97	1–35.75	0.051
iPSA > 11	1.57	0.67–3.69	0.3	3.87	0.64–23.28	0.14
Gleason score > 8	1.35	0.5–3.68	0.55	2.7	0.3–24.17	0.37
D Amico Score > 2	1.46	0.53–3.97	0.46	1.38	0.15–12.41	0.77
PSMA-TV	0.96	0.89–1.04	0.31	1.16	1.05–1.28	0.003
PSMA-TLU	0.998	0.992–1.004	0.45	1.005	1.002–1.009	0.004
SUVmax	1	0.98–1.019	0.97	0.97	0.89–1.06	0.48
ASP	0.99	0.96–1.02	0.52	1.05	1.02–1.07	< 0.001
	LRC			LC
Age > 74 y	0.36	0.08–1.6	0.18	3.23	0.4–26.41	0.27
iPSA > 11	3.62	0.99–13.17	0.051	7.58	0.93–61.67	0.058
Gleason score > 8	1.62	0.5–5.28	0.42	1.62	0.32–8.04	0.56
D Amico Score > 2	1.36	0.37–5.02	0.65	1.39	0.28–6.96	0.69
PSMA-TV	0.98	0.9–1.07	0.64	0.98	0.88–1.09	0.73
PSMA-TLU	0.999	0.993–1.005	0.75	0.993	0.977–1.009	0.39
SUVmax	1.004	0.981–1.028	0.72	0.97	0.91–1.04	0.41
ASP	0.995	0.959–1.032	0.79	0.991	0.942–1.043	0.73

PET parameters were included as metric parameters. Bold p values indicate significance (p < 0.05)

ISSN: 1748-717X