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Table 1 Patient’s characteristics

From: Re-irradiation of anaplastic meningioma: higher dose and concomitant Bevacizumab may improve progression-free survival

n

34

Age

57.2y (37–74)

Location of primary tumor

 

Frontal

Parietal

Temporal

Occipital

Base of skull

18

10

4

1

1

Type of resection 1st surgery (Simpson)

 

1–2

3–4

5

12

20

2

Reason for WHO 3

 

Histopathology criteria

CDKN2A deletion

Mitotic > 20

16

10

24

1p loss (more than 50%)

55.8%

Karnofsky status

80 (70–100)

Total dose deliver 1st

60 Gy (54–60)

2nd surgery (yes)

25 (73%)

Total dose deliver 2nd

35 Gy (25-40.05)

Number of fractions

10 (5–15)

BED 2nd RT (α/β = 10) Median, range

48.8 (31.2–56)

Bed > 50 Gy

16 (47%)

concomitant Bevacizumab (yes)%

12 (35.3%)

PTV 2ND RT

35 cc (11.5-212.4 cc)

Median follow up (range)

13 (5–28 months)