Table 2 Univariate and multivariate analyses results of local failure from MRI evaluation

Over 65% volume reduction at MRI evaluation

No

1

< 0.01

1

< 0.01

Yes

0.33

(0.15–0.74)

0.35

(0.16–0.76)

Over 90% volume reduction at MRI evaluation

No

1

0.03

1

0.04

Yes

0.38

(0.16–0.91)

0.41

(0.17–0.97)

each GTV (cc)

0.3–1

1

< 0.01

1

< 0.01

1

< 0.01

1

0.02

1

0.01

> 1

4.62

(1.56–13.68)

4.48

(1.50–13.37)

4.37

(1.48–12.88)

3.72

(1.28–10.83)

4.12

(1.39–12.25)

Age (years)

22–65

1

0.70

> 65

0.84

(0.35–2.00)

PS

0–1

1

0.17

2–3

1.80

(0.78–4.17)

Primary cancer

Lung and breast

1

0.66

Others

1.23

(0.49–3.09)

GTV dose

D80 < 42 Gy

1

< 0.01

1

0.01

D80 > 42 Gy

0.27

(0.12–0.61)

0.37

(0.17–0.81)

GTV dose

D98 < 39 Gy

1

0.04

1

0.22

D98 > 39 Gy

0.40

(0.17–0.96)

0.58

(0.25–1.38)