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Table 1 Study design according to the Population, Intervention, Control, Outcome, Study Design (PICOS) method

From: Advances in breast cancer treatment: a systematic review of preoperative stereotactic body radiotherapy (SBRT) for breast cancer

Population

Patients treated with preoperative stereotactic body radiotherapy (SBRT) for breast cancer

Intervention

SBRT to the primary tumor (fraction dose ≥ 5 Gy)

Control

Not applicable (the data will be pooled from single arm trials)

Outcome

Primary: early toxicity, cosmesis

Secondary: rates of pathologic complete response (pCR), late toxicity

Study design

Any retrospective or prospective original studies describing clinical outcomes of patients treated with preoperative SBRT for primary breast cancer

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Radiation Oncology

ISSN: 1748-717X

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