Table 5 Comparison of the safety of radiotherapy dose 50.4Â gy and 61.2Â gy in elderly patients with ESCC
From: Radiotherapy with S-1 for the treatment of esophageal squamous cell carcinoma 75 years or older
Adverse effects | 50.4 Gy(n = 37) | 61.2 Gy(n = 54) | P-value | ||||
|---|---|---|---|---|---|---|---|
Grade 1 ~ 2 | Grade 3 | Grade 4 | Grade 1 ~ 2 | Grade 3 | Grade 4 | ||
Leukopenia | 13(35.1) | 3(8.1) | 1(2.7) | 17(31.5) | 5(9.3) | 1(2.0) | 0.752 |
Neutropenia | 8(21.6) | 1(2.7) | 0 | 15(27.8) | 2(3.7) | 1(2.0) | 0.355 |
Thrombocytopenia | 13(35.1) | 2(5.4) | 0 | 13(24.1) | 1(2.0) | 0 | 0.142 |
Anemia | 23(62.2) | 0 | 0 | 17(31.5) | 1(2.0) | 0 | 0.004# |
Esophagitis | 22(59.5) | 0 | 0 | 42(77.8) | 0 | 0 | 0.060 |
Pneumonitis | 14(37.8) | 0 | 0 | 28(51.9) | 0 | 0 | 0.249 |
Dermatitis | 2(5.4) | 0 | 0 | 11(20.4) | 0 | 0 | 0.045 |