Dose escalation in radical radio(chemo)therapy for cervical and upper thoracic esophageal cancer with 3DCRT/IMRT (ChC&UES): a multicenter retrospective study

Table 3 Treatment efficacy according to radiation dose

Treatment efficacy	SD (≤55 Gy)	HD-conventional (55–63 Gy)	HD-ultra (≥ 63 Gy)	χ²	P
Cervical ESCA				6.635	0.036
ORR	50% (12) a*	68.7% (103) a, b*	79.6% (39)b*
Non-ORR	50% (12) a*	31.3% (47) a, b*	20.4% (10)b*
Upper thoracic ESCA				8.204	0.017
ORR	57.0% (61)a*	64.8% (302) a, b*	74.4% (99)b*
Non-ORR	43.0% (46)a*	35.2% (164) a, b*	25.6% (34)b*

ESCA: Esophageal cancer; SD: Standard dose; HD: High dose; OR: Objective response rate; Non-OR: Non-objective response rate
*: Each subscript letter denotes a subset of radiation dose categories whose column proportions do not differ significantly from each other at the 0.05 level

ISSN: 1748-717X