Table 2 Comparison of radiotherapy operation between IMRT combined with 3D postloading radiotherapy group and IMRT combined with freehand insertion postloading radiotherapy group
From: 3D-printed brachytherapy in patients with cervical cancer: improving efficacy and safety outcomes
Variables | 3D brachytherapy | Freehand implant brachytherapy | χ2/H/t | P-value | |
|---|---|---|---|---|---|
(n = 120) | (n = 132) | ||||
Number of planting needles [% (n)] | 9.998 | < 0.001*** | |||
0 | 0.0% (0) | 6.0% (8) | |||
1 | 0.0% (0) | 1.5% (2) | |||
2 | 26.7% (32) | 82.6% (109) | |||
3 | 25.0% (30) | 2.3% (3) | |||
4 | 22.5% (27) | 6.1% (8) | |||
5 | 21.7% (26) | 1.5% (2) | |||
7 | 4.1% (5) | 0.0% (0) | |||
Number of CT scans [% (n)] | -4.630 | < 0.001*** | |||
1 | 97.5% (117) | 78.0% (103) | |||
2 | 2.5% (3) | 21.2% (122) | |||
3 | 0.0% (0) | 0.8% (1) | |||
Vaginal tamponade for intraoperative bleeding [% (n)] | 3.332 | 0.068 | |||
Yes | 95.0% (114) | 88.6% (117) | |||
No | 5.0% (6) | 11.4% (15) | |||
CTV longitudinal diameter (cm, \(\:\stackrel{-}{x}\)±s) | 4.30 ± 1.44 | 4.40 ± 1.12 | 0.612 | 0.541 | |
CTV volume (cm3, \(\:\stackrel{-}{x}\)±s) | 67.24 ± 52.93 | 52.28 ± 26.54 | -2.973 | 0.006** | |
Furthest distance from the longitudinal line of the uterine cavity outside the target area (cm, \(\:\stackrel{-}{x}\)±s) | 1.96 ± 0.74 | 1.39 ± 0.46 | -7.310 | < 0.001*** | |
CTV-D95 (Gy, \(\:\stackrel{-}{x}\)±s) | 53.08 ± 1.23 | 51.91 ± 2.03 | -5.599 | < 0.001*** | |
CTV-D98 (Gy, \(\:\stackrel{-}{x}\)±s) | 46.91 ± 2.26 | 45.29 ± 3.21 | -4.662 | < 0.001*** | |
CTV-D100 (Gy, \(\:\stackrel{-}{x}\)±s) | 33.92 ± 4.21 | 32.25 ± 4.58 | -3.007 | 0.003** | |
CTV-v100 (%, \(\:\stackrel{-}{x}\)±s) | 85.05 ± 5.95 | 90.48 ± 9.50 | 5.484 | < 0.001*** | |
CTV-v150 (%, \(\:\stackrel{-}{x}\)±s) | 61.80 ± 4.23 | 64.76 ± 5.97 | 4.563 | < 0.001*** | |
CTV-v200 (%, \(\:\stackrel{-}{x}\)±s) | 41.65 ± 5.63 | 44.69 ± 7.77 | 3.523 | < 0.001*** | |
Bladder irradiation dose D1CC (Gy, \(\:\stackrel{-}{x}\)±s) | 50.82 ± 10.42 | 60.39 ± 16.91 | 5.461 | < 0.001*** | |
Bladder irradiation dose D2CC (Gy, \(\:\stackrel{-}{x}\)±s) | 47.02 ± 9.13 | 54.40 ± 15.15 | 4.732 | < 0.001*** | |
Rectal irradiation dose D1CC (Gy, \(\:\stackrel{-}{x}\)±s) | 51.99 ± 55.44 | 58.22 ± 17.33 | 1.227 | 0.221 | |
Rectal irradiation dose D2CC (Gy, \(\:\stackrel{-}{x}\)±s) | 42.53 ± 12.17 | 51.47 ± 15.11 | 5.191 | < 0.001*** |