Fig. 4

Correlations of dynamics of circulating cell-free tumor DNA (ctDNA) (ādeclineā versus ālate shedding or persistenceā) and the proof of ctDNA at the end of treatment in week 5 / 6 with the pre-therapeutic magnetic resonance imaging (MRI) volumes (tumor volumes pre tx (cc)) (A and B), the absolute tumor volume change in week 2 (C and D) and MRI tumor volume decrease between baseline and week 5 (E and F)