Table 3 Univariate analysis for overall survival rate using Cox proportional hazards model
From: Respiratory-gated proton beam therapy for intrahepatic cholangiocarcinoma without fiducial markers
Variables | Strata | Patient number | Univariate analysis | ||
|---|---|---|---|---|---|
| Â | Â | Â | HR | 95%CI | p-value |
Sex (M = 1, F = 0) | F | 8 | 1 | (referent) | – |
|  | M | 16 | 0.835 | 0.301–2.310 | 0.728 |
Age >  = 75 ~ 1,  < 75 ~ 0 |  < 75 | 16 | 1 | (referent) | – |
|  | 75 <  =  | 8 | 1.118 | 0.405–3.088 | 0.83 |
C-P A = 0, BorC = 1 | normal-A | 21 | 1 | (referent) | – |
|  | B-C | 3 | 3.12 | 0.614–15.86 | 0.17 |
Distance from GI-tract > 20 mm = 1,  < 20 mm = 0 |  < 2 cm | 8 | 1 | (referent) | – |
|  | 2 cm <  =  | 16 | 0.932 | 0.329–2.639 | 0.895 |
Tumor diameter >  = 5 ~ 1, < 5 ~ 0 |  < 5 cm | 16 | 1 | (referent) | – |
|  | 5 cm <  =  | 8 | 0.742 | 0.252–2.181 | 0.587 |
T1 or T2 = 0, T3 or T4 = 1 | T1–T2 | 19 | 1 | (referent) | – |
|  | T3–T4 | 5 | 1.368 | 0.439–4.260 | 0.589 |
N | 0 | 20 | 1 | (referent) | – |
|  | 1 | 4 | 1.747 | 0.493–6.190 | 0.388 |
Stage (1, 2 = 0, 3,4 = 1) | Stage1–2 | 15 | 1 | (referent) | – |
|  | Stage3–4 | 9 | 1.53 | 0.567–4.130 | 0.401 |
Concurrent Chemo Yes = 1, No = 0 | No | 16 | 1 | (referent) | – |
|  | Yes | 8 | 1.25 | 0.431–3.623 | 0.681 |
Adjuvant | No | 11 | 1 | (referent) | – |
|  | Yes | 13 | 0.795 | 0.296–2.135 | 0.649 |