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Table 1 Comparison of patient and tumor characteristics between the two study groups

From: Outcomes of definitive radiotherapy vs. laryngectomy followed by adjuvant radiotherapy in patients with locally advanced laryngeal squamous cell carcinoma: real-world experience in a referral cancer center

Variable

Categories

Definitive

Adjuvant

P-value*

T stage

T3

46 (71.9)

21 (58.3)

0.112

T4a

13 (21.3)

14 (40)

T4b

2 (3.3)

0 (0)

N stage

0

31 (48.4)

16 (44.4)

0.884

1

10 (15.6)

5 (13.9)

2

18 (28.1)

13 (36.1)

3

5 (7.8)

2 (5.6)

Stage

III

32 (50)

13 (36.1)

0.300

IVa

27 (42.2)

21 (58.3)

IVb

5 (7.8)

2 (5.6)

Completion of RT

Yes

58 (90.6)

31 (86.1)

0.498

No

6 (9.4)

5 (13.9)

Chemotherapy before RT

Yes

11 (17.2)

4 (11.1)

0.414

No

53 (82.8)

32 (88.9)

Concurrent systemic therapy

Yes

55 (85.9)

18 (50)

< 0.001

No

9 (14.1)

18 (50)

Regimen of concurrent systemic therapy

Cisplatin, weekly

33 (60)

16 (88.9)

0.108

Cisplatin, triweekly

20 (36.4)

2 (11.1)

Erbitux

2 (3.6)

0

Systemic therapy compliance

(when indicated)

Yes

38 (69.1)

7 (38.8)

< 0.001

No

17 (30.9)

11 (61.2)

  1. *The result of the chi-square test