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Fig. 1 | Radiation Oncology

Fig. 1

From: Alpha/beta values in pediatric medulloblastoma: implications for tailored approaches in radiation oncology

Fig. 1

Modelled survival curves plotted against determined recurrence data of medulloblastoma cell lines

Probability of recurrence after fractionated irradiation as determined by non-linear regression of survival data of the medulloblastoma cell lines ONS76 (A), UW228-3 (B), DAOY (C), D283 (D), D425 (E) as well as the breast cancer cell line MCF-7 (F) as a control with a low alpha/beta value. The solid lines depict the derived estimated survival curves for the denoted amount of cells after splitting of the full dose D (x-axis) in 2 (orange), 4 (green) or 8 (blue) fractionations. The coloured dashed lines represent the corresponding high and low 95% confidence intervals. The actual determined data for the chosen conditions (lower cell number and 2, 4, and 8 fractions) is shown as open diamond (2x fract.), square (4x fract.) and triangle (8x fract.) data points using the same colour code

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Radiation Oncology

ISSN: 1748-717X

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