Fig. 4
From: Estimation of adaptive radiation therapy requirements for rectal cancer: a two-center study
(a)-(d) The ROC curves of the univariant model for PTVvol, HI, Frac_dose, Accmulated_dose in 109 internal validation datasets. (e) The ROC curves of the multivariant models in 109 internal validation datasets with AUC = 0.76. (f) The ROC curves of the multivariant models in 134 external validation datasets with AUC = 0.68. Light blue regions were the 95% CI. The red points indicate the best threshold by making sum of sensitivity and specificity maximum, and blue point indicates a threshold that may be clinically applicable. In parentheses is their corresponding cut-off value