Assessing intra- and interfraction motion and its dosimetric impacts on cervical cancer adaptive radiotherapy based on 1.5T MR-Linac

Table 3 Dose–volume parameters of the PTV

Parameters	PlanA	PlanA1	PlanA2	ANOVA P value	P value
Parameters	PlanA	PlanA1	PlanA2	ANOVA P value	PlanA vs. PlanA1	PlanA vs. PlanA2	PlanA1 vs. PlanA2
Volume (ml)	849.27 ± 235.99	903.58 ± 244.91	912.34 ± 255.86	0.339	0.473	0.491	1.000
D1 cc (Gy)	59.99 ± 1.54	59.66 ± 1.55	58.06 ± 1.57	0.425	0.637	0.637	1.000
D2 (Gy)	58.06 ± 1.19	57.77 ± 1.15	57.77 ± 1.18	0.368	0.562	0.507	1.000
D50 (Gy)	53.56 ± 0.38	53.21 ± 0.42	53.17 ± 0.51	0.000*	0.000*	0.000*	1.000
D98 (Gy)	48.54 ± 6.47	41.04 ± 10.74	41.00 ± 11.01	0.000*	0.000*	0.000*	1.000
Dmean (Gy)	53.62 ± 0.50	52.63 ± 1.01	52.65 ± 1.19	0.000*	0.000*	0.000*	1.000
Dmax (Gy)	61.65 ± 1.75	60.93 ± 1.72	60.92 ± 1.76	0.098	0.134	0.108	1.000
Dmin (Gy)	34.98 ± 13.39	19.04 ± 13.55	19.58 ± 13.90	0.000*	0.000*	0.000*	1.000
HI	1.22 ± 0.07	1.20 ± 0.06	1.20 ± 0.07	0.073	0.094	0.081	1.000
CI	1.12 ± 0.30	1.05 ± 0.35	1.03 ± 0.31	0.919	1.000	1.000	1.000

PlanA, CT plan; PlanA1, Mapping the planA dose distribution to the pre-MR image. PlanA2, Mapping the planA dose distribution to the post-MR image. Dx represents the dose received by X% of the target volume; Dmax, maximum dose; Dmean, mean dose; Dmin, minimum dose; HI, heterogeneity index; and CI, conformity index. * represents a statistically significant difference

ISSN: 1748-717X