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Table 1 The baseline characteristics of all the included studies

From: Efficacy and safety of proton radiotherapy in treating choroidal melanoma: a systematic review and meta-analysis

Study

Study type

Research year range

N

Age (mean range or s)

Gender

(M/F)

Tumor size (mm)

Treatment total dose

Median follow-up (months)

Eric Tran 2012 [37]

Retrospective study

1995–

2007

59

59 (34–86)

(39/20)

11. 4

(6.8–17)

32%:54 CGE,

68%: 60 CGE

63

(4–131)

Kim TW 2018 [33]

Retrospective study

2009–

2015

24

62 (44–85)

(14/10)

11

(4.4–16)

60–70 CGE

36.5

(9–82)

Papakostas TD 2017 [35]

Retrospective study

1985.01–

1997.12

336

61 (24–90)

(186/150)

18

(9.0–24.0)

70 Gy

84

(2. 8– 286.8)

Bensoussan E 2016 [36]

Retrospective study

1991.06–

2015.06

492

Average:

62. 4

(19–89)

(258/234)

Average:

14. 91

(7–24.1)

60 Gy

Average:

61.9

Fuss M 2001 [38]

Retrospective study

1990.10–

1998.11

78

61(26–89)

(44/34)

10

70. 2 CGE

(median dose)

34 (6–102)

Carlo Mosci 2012 [34]

Retrospective study

1996.08–

2007.07

70

Average:

62.7

(48.6–76.8)

(43/27)

Average:

15.2

(12. 5–17.9)

60 Gy

52.9

(14.6–107.6)