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Table 2 Prognostic value of ΔALC in different subgroups

From: The impact of radiation-related lymphocyte recovery on the prognosis of locally advanced esophageal squamous cell carcinoma patients: a retrospective analysis

Factors

Median OS (months)

Median PFS (months)

Group A

Group B

p value

Group A

Group B

p value

Combined chemotherapy

Yes

17.9

20

0.24

10.1

12.7

0.08

No

9.7

14.0

0.0017

7.9

9.3

0.052

Tumor length

≤ 5 cm

21.1

42.2

0.063

10.0

17.4

0.144

> 5 cm

12.8

14.4

0.23

8.4

11.1

0.095

Tumor location

Cervical + Upper thoracic

21.1

37.1

0.383

10.0

13.3

0.431

Middle + Lower thoracic

12.2

18.4

0.007

7.8

11.4

0.006

T stage

< 3

18.5

46.6

0.167

10.7

42.2

0.140

≥ 3

12.5

14.4

0.113

7.9

10.17

0.133

N stage

< 2

19.0

42.2

0.230

10.7

31.9

0.683

≥ 2

12.5

16.1

0.079

7.8

12.1

0.012

TNM stage

II-III

12.5

42.2

0.004

10.0

16.5

0.026

IVa

18.7

14.0

0.466

7.5

10.0

0.560

minALC*

G1-3

15.5

27.8

0.014

8.4

13.0

0.014

G4

10

14.4

0.012

8.4

7.8

0.62

  1. OS: Overall survival, PFS: Progression-free survival. *Graded by Common Terminology Criteria for Adverse Events version 5.0