Cardiac substructure dose distributions in node-positive and node-negative breast cancer patients undergoing 3D-CRT: comparing the predictive accuracy of mean heart dose and mean left ventricular dose

Table 2 Linear regression coefficient values between MHD and MLVD versus the cardiac substructures for node-positive and node negative BC patients

Independent variable	Dependent variable	Coefficient of determination
		Node-positive BC patients		Node-negative BC patients
		R²	P value	R²	P value
MHD	MRV	0.489	< 0.001	0.54	0.007)
MHD	MLA	0.15	0.005	0.04	< 0.001)
MHD	MRA	0.031	< 0.283	0.05	0.374)
MHD	MLADCA	0.40	< 0.001	0.27	< 0.001)
MHD	MRC	0.096	0.055	0.42	< 0.001)
MHD	MLCX	0.10	0.061	0.12	0.037)
MLVD	MRV	0.60	< 0.001	0.58	< 0.001)
MLVD	MLA	0.16	0.012	0.01	0.013)
MLVD	MRA	0.29	< 0.001	0.20	0.005)
MLVD	MLADCA	0.45	< 0.001	0.30	< 0.03)
MLVD	MRC	0.22	0.002	0.54	0.007)
MLVD	MLCX	0.10	0.131	0.04	< 0.001)

(MHD = mean heart dose, MLVD = mean left ventricular dose, MRV = mean right ventricle, MRA = mean right atrium, MLA = mean left atrium, MLADCA = mean left anterior descending coronary artery, MLCx = mean left circumflex artery, MRC = mean right coronary artery)

ISSN: 1748-717X