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Table 1 Dose and dose-volume criteria for PTV and oars for arms A and B

From: Dummy run study for outlining and plan quality of intensity-modulated radiotherapy in elderly patients with newly diagnosed glioblastoma: The Japan clinical oncology group study JCOG1910 (AgedGlio-PIII)

Structure

Dose-volume criteria

Arm A

Arm B

Per protocol

Acceptable variation

Per protocol

Acceptable variation

PTV

V90%

≥ 98%

≥ 95%

≥ 98%

≥ 95%

D50%

98% ≤, ≤ 102%

95% ≤, ≤ 105%

98% ≤, ≤ 102%

95% ≤, ≤ 105%

D2%

≤ 107%

≤ 110%

≤ 107%

≤ 110%

Retina_L or Retina_R

D2%

≤ 39.0 Gy

-

≤ 25.4 Gy

-

Brain Stem

D33.3%

≤ 46.8 Gy

-

≤ 30.0 Gy

-

D66.7%

≤ 43.3 Gy

-

≤ 27.9 Gy

-

D98%

≤ 41.7 Gy

-

≤ 27.0 Gy

-

Spinal Cord

D2%

≤ 41.7 Gy

-

≤ 27.0 Gy

-

Cerebrum

D33.3%

≤ 46.8 Gy

-

≤ 30.0 Gy

-

D66.7%

≤ 43.8 Gy

-

≤ 28.2 Gy

-

Optic Nerve_L or

Optic Nerve_R

D2%

≤ 43.8 Gy

-

≤ 28.2 Gy

-

Chiasim

D2%

≤ 43.8 Gy

-

≤ 28.2 Gy

-

Lens_L or Lens_R

D2%

< 13.7 Gy

-

< 10.0 Gy

-

  1. PTV, planning target volume; OAR, organ at risk