Table 3 Relationship between tobacco consumption and degree of toxicity
From: Smoking increases breast toxicity despite adjuvant hypofractionated IMRT in early breast cancer
Smokers (n, %) (n = 177) | Non-Smokers (n, %) (n = 389) | Total (n, %) (n = 566) | Regression coefficient | P value | CI (95%) | |
|---|---|---|---|---|---|---|
Acute radiodermatitis | ||||||
No | 9 (5.1%) | 30 (7.7%) | 39 (6.9%) | -2.477 | < 0,001 | -2.828, -2.126 |
Grade 1 | 155 (87.6%) | 341 (87.7%) | 496 (87.6%) | 3.016 | < 0,001 | 2.591, 3.440 |
Grade 2 | 0 (0.0%) | 31 (7.9%) | 31 (5.5%) | 5.281 | < 0.001 | 4.135, 6.427 |
Grade ≥ 3 | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | |||
Smokers (n, %) (n = 155) | Non-Smokers (n, %) (n = 334) | Total (n, %) (n = 486) | Regression coefficient | P value | CI (95%) | |
Fibrosis | ||||||
No | 90 (58.1%) | 238 (71.3%) | 328 (67.1%) | -0.146 | 0.014 | -0.262, -0.030 |
Grade 1 | 44 (28.3%) | 90 (27.0%) | 134 (27.4%) | 3.032 | < 0.001 | 2.612, 3.451 |
Grade 2 | 18 (11.6%) | 6 (1,8%) | 24 (4.9%) | 5.281 | < 0.001 | 4.135, 6.427 |
Grade 3 | 3 (1.9%) | 0 (0.0%) | 3 (0.6%) | 6.000 | 0.001 | 2.000, 10.000 |
Grade 4 | 0 (0%) | 0 (0.0%) | 0 (0%) | |||