Table 2 A list of the discussed equations/radiobiology models for easy reference
From: Mathematical modeling in radiotherapy for cancer: a comprehensive narrative review
Equation | Name | Description |
|---|---|---|
1 | Linear-quadratic (LQ) model | Classical cell survival model to model cell survival as a function of radiation dose |
2 | Biologically effective dose (BED) | Applies the LQ model for dose and fractionation effects |
3 | Tumor control probability (TCP) | Predicts tumor eradication likelihood |
4 | Normal tissue complication probability (NTCP) | Estimates radiation-induced normal tissue toxicity risk |
5 | Equivalent uniform dose (EUD) | Converts non-uniform dose to an equivalent uniform dose |
6 | Single-hit model | Alternate cell survival model that assumes cell death from a single lethal event |
7 | Multi-target, single-hit model | Alternate cell survival model that accounts for multiple sublethal targets per cell |
8 | Lethal-potentially lethal (LPL) model | Alternate cell survival model that includes repairable sublethal and lethal damage |
9 | Oxygen enhancement ratio (OER) | Quantifies oxygen’s impact on radiation sensitivity |
10 | Relative biological effectiveness (RBE) | Compares effectiveness of different radiation types |