Fig. 2

Identification of optimal threshold of DVH parameters for the prevention of symptomatic RP. (A) Correlation analyses between V20, MLD, and V5 in the whole cohort. (B) Correlation analyses between V20, MLD, and V5 in the immune-RT cohort. (C) Receiver operating characteristic curve (ROC) analysis of V20 in the prediction of grade ≥ 2 RP in the immune-RT cohort. (D) Incidence of grade ≥ 2 RP in patients stratified by V20 at 20% in the immune-RT subgroup, No ICI subgroup and the validating cohort