Fig. 2

HNSCC subsites, distribution of recurrence types and cumulative incidence of locoregional recurrence for HPV- HNSCC. (A) Pie chart depicting proportions of HNSCC subsites of the entire dataset, including the relative fraction of recurrences. (B) Pie chart depicting the distribution of predominant typology of recurrence, including the location of type C/D low-dose recurrences. (C) Venn diagram depicting pattern of local/regional recurrence and distant metastasis (D) Cumulative incidence of locoregional recurrences for HPV- HNSCC, taking competing risk into account. HNSCC = head and neck squamous cell carcinoma, OCSCC = oral cavity squamous cell carcinoma, OPSCC = oropharyngeal squamous cell carcinoma, HPSCC = hypopharyngeal squamous cell carcinoma, LSCC = laryngeal squamous cell carcinoma, HPV = human papillomavirus, DM = distant metastasis, LR = local recurrence, RR = regional recurrence, ex. = excluding, mos.= months