Table 3 Patient and disease characteristics
Recurrence population, excluding DM only | n = 40 | (%) |
|---|---|---|
Age | ||
Median (range), years | 66.0 | (23–86) |
Gender | ||
Female | 16 | (40.0) |
Male | 24 | (60.0) |
Tumor site | ||
Oral Cavity | 33 | (82.5) |
Oral Tongue | 11 | (27.5) |
Buccal Mucosa | 1 | (2.5) |
Floor of Mouth | 5 | (12.5) |
Upper/Lower Alveolar Ridge and Gingiva | 16 | (40.0) |
Oropharynx (p16-) | 1 | (2.5) |
Hypopharynx | 2 | (5.0) |
Larynx | 4 | (10) |
Histologic differentiation | ||
Poor | 7 | (17.5) |
Moderate | 32 | (80.0) |
Well | 0 | |
p16+ | 1 | (2.5) |
Pathological T stage | ||
T1 | 3 | (7.5) |
T2 | 4 | (10.0) |
T3 | 10 | (25.0) |
T4a | 22 | (55.0) |
T4b | 1 | (2.5) |
Pathological N stage | ||
No dissection | 1 | (2.5) |
N0 | 12 | (30.0) |
N1 | 5 | (12,5) |
N2a | 1 | (2,5) |
N2b | 5 | (12,5) |
N2c | 1 | (2,5) |
N3a | 0 | |
N3b | 15 | (37.5) |
Overall stage | ||
Stage I | 0 | |
Stage II | 1 | (2.5) |
Stage III | 5 | (12.5) |
Stage IVa | 19 | (47.5) |
Stage IVb | 15 | (37.5) |
Primary surgery margin status | ||
Negative (> 5 mm) | 10 | (25.0) |
Close (1–5 mm) | 17 | (42.5) |
Positive | 11 | (27.5) |
Unspecified | 2 | (5.0) |
Depth of invasion | ||
≤ 5 mm | 4 | (10.0) |
> 5 mm ≤ 10 mm | 8 | (20.0) |
> 10 mm | 17 | (42.5) |
Unspecified | 11 | (27.5) |
Perineural invasion | ||
Yes | 18 | (45.0) |
No | 17 | (42.5) |
Unspecified | 5 | (12.5) |
Lymphovascular invasion | ||
Yes | 23 | (57.5) |
No | 17 | (42.5) |
Extracapsular extension | ||
Yes | 15 | (55.5) |
No | 12 | (44.5) |