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Table 2 The weekly volume and DSC of OARs and target volumes for 23 NPC patients included in this study

From: Real-time morphological and dosimetric adaptation in nasopharyngeal carcinoma radiotherapy: insights from autosegmented fractional fan-beam CT

Structures

Week 1

(cm3)

Week 2

(cm3)

Week 3

(cm3)

Week 4

(cm3)

Week 5

(cm3)

Week 6

(cm3)

Week 7

(cm3)

Average

(cm3)

Range of fluctuation

(cm3, %)

Volume (cm3)

         

GTVp

31.60

30.67

29.93

29.30

29.25

29.35

29.17

29.90

-0.73 ∼ 1.77 (-2.44 ∼ 5.69)

GTVns

5.44

4.81

4.14

3.21

2.91

2.38

2.24

3.59

-1.35 ∼ 1.85 (-37.60 ∼ 51.53)

CTV1

85.40

83.72

82.09

81.81

81.47

81.34

81.06

82.41

-1.35 ∼ 2.99 (-1.63 ∼ 3.63)

CTV2

455.01

445.48

445.97

439.17

433.42

428.45

424.68

438.88

-14.20 ∼ 16.13 (-3.24 ∼ 3.68)

Parotids

34.90

32.55

32.13

29.89

28.00

26.87

26.33

31.10

-3.77 ∼ 4.80 (-12.52 ∼ 15.95)

Submandibulars

9.14

8.59

8.41

7.83

7.42

7.33

7.36

8.01

-0.68 ∼ 1.14 (-8.49 ∼ 14.11)

Thyroid

16.37

16.42

16.37

16.20

15.95

15.65

15.29

16.04

-0.75 ∼ 0.38 (-4.68 ∼ 2.37)

Larynx_Supraglottic

8.70

8.66

8.76

8.66

8.64

8.82

8.64

8.60

-0.06 ∼ 0.06 (-0.69 ∼ 0.69)

Larynx_Glotticx

5.62

5.69

5.63

5.69

5.73

5.64

5.69

5.67

-0.05 ∼ 0.06 (-0.88 ∼ 1.06)

OralCavity

196.19

195.97

195.85

196.58

194.65

196.16

196.56

195.99

-1.34 ∼ 0.59 (-0.68 ∼ 0.30)

Chiasm

0.76

0.76

0.74

0.75

0.74

0.76

0.76

0.75

-0.01 ∼ 0.01 (-1.73 ∼ 1.33)

OpticNerves

0.47

0.48

0.48

0.48

0.48

0.48

0.47

0.48

-0.01 ∼ 0 (-2.08 ∼ 0)

Lenses

0.20

0.21

0.20

0.20

0.20

0.20

0.20

0.20

0 (0)

Eyes

8.76

8.75

8.71

8.71

8.71

8.65

8.68

8.71

-0.06 ∼ 0.04 (-0.69 ∼ 0.46)

BraiStem

35.73

35.80

36.41

36.18

36.40

36.12

36.10

36.11

-1.37 ∼ 0.47 (-1.05 ∼ 0.83)

SpinalCord

21.52

21.03

20.94

21.24

21.34

21.47

21.44

21.28

-0.34 ∼ 0.24 (-1.17 ∼ 1.60)

TemporalLobes

113.93

113.28

113.02

114.76

114.85

114.46

114.14

113.78

-1.04 ∼ 0.79 (-0.91 ∼ 0.69)

Mandibles*

48.82

49.17

49.41

49.43

49.4

49.32

49.22

49.25

-

TMJs*

2.11

2.13

2.13

2.12

2.08

2.1

2.09

2.10

-

TympanicCavities*

0.57

0.56

0.56

0.55

0.55

0.56

0.55

0.56

-

Cochleas*

0.04

0.04

0.04

0.04

0.04

0.04

0.04

0.04

-

ETs*

0.15

0.16

0.16

0.14

0.15

0.15

0.15

0.15

-

Pituitary*

0.18

0.17

0.17

0.17

0.16

0.16

0.17

0.17

-

IACs*

0.10

0.10

0.11

0.10

0.09

0.10

0.10

0.10

-

Vestibul semises*

0.26

0.26

0.25

0.25

0.26

0.25

0.25

0.25

-

DSC

         

GTVp

0.90

0.89

0.88

0.88

0.89

0.89

0.88

0.89

-0.01 ∼ 0 0.01 (-1.12 ∼ 1.12)

GTVns

0.61

0.55

0.52

0.45

0.42

0.38

0.33

0.47

-0.14 ∼ 0 0.14 (-29.79 ∼ 29.79)

CTV1

0.94

0.94

0.94

0.94

0.94

0.94

0.94

0.94

0 (0)

CTV2

0.93

0.92

0.90

0.89

0.88

0.87

0.86

0.89

-0.03 ∼ 0.04 (-3.37 ∼ 4.49)

Parotids

0.84

0.85

0.84

0.83

0.8

0.77

0.76

0.81

-0.05 ∼ 0 0.04 (-6.17 ∼ 4.94)

Submandibulars

0.83

0.83

0.8

0.78

0.76

0.75

0.74

0.78

-0.04 ∼ 0 0.05 (-5.13 ∼ 6.41)

Thyroid

0.78

0.74

0.72

0.70

0.71

0.70

0.69

0.72

-0.03 ∼ 0 0.06 (-4.17 ∼ 8.38)

Larynx_Supraglottic

0.46

0.41

0.44

0.40

0.45

0.43

0.41

0.43

-0.03 ∼ 0.03 (-6.98 ∼ 6.98)

Larynx_Glotticx

0.78

0.69

0.62

0.63

0.62

0.62

0.63

0.66

−0.04 ∼ 0 0.12 (−6.06 ∼ 18.18)

OralCavity

0.92

0.92

0.92

0.92

0.92

0.92

0.92

0.92

0 (0)

Chiasm

0.55

0.58

0.61

0.55

0.59

0.53

0.54

0.56

-0.03 ∼ 0.05 (-5.36 ∼ 8.93)

OpticNerves

0.58

0.57

0.56

0.56

0.56

0.57

0.53

0.56

-0.03 ∼ 0 0.02 (-5.36 ∼ 3.67)

Lenses

0.61

0.61

0.6

0.58

0.57

0.57

0.52

0.58

-0.06 ∼ 0.03 (-10.34 ∼ 5.17)

Eyes

0.89

0.89

0.89

0.89

0.88

0.88

0.87

0.88

-0.01 ∼ 0.01 (-1.14 ∼ 1.14)

BraiStem

0.88

0.89

0.89

0.89

0.88

0.88

0.88

0.88

0 ∼ 0.01 (0 ∼ 1.14)

SpinalCord

0.80

0.77

0.73

0.72

0.69

0.71

0.70

0.73

-0.04 ∼ 0 0.07 (-5.48 ∼ 9.59)

TemporalLobes

0.91

0.91

0.92

0.9

0.91

0.9

0.9

0.91

-0.01 ∼ 0 0.01 (-1.11 ∼ 1.11)

Mandibles

0.86

0.86

0.86

0.86

0.86

0.84

0.85

0.86

-0.02 ∼ 0 (-2.33 ∼ 0)

TMJs

0.51

0.5

0.52

0.49

0.51

0.49

0.48

0.50

-0.02 ∼ 0 0.02 (-4.00 ∼ 4.00)

TympanicCavities

0.81

0.79

0.74

0.79

0.79

0.78

0.77

0.78

−0.04 ∼ 0 0.03 (−5.13 ∼ 3.85)

Cochleas

0.50

0.50

0.55

0.50

0.54

0.48

0.49

0.51

−0.03 ∼ 0 0.04 (−5.88 ∼ 7.84)

ETs

0.63

0.64

0.61

0.59

0.63

0.61

0.58

0.61

−0.03 ∼ 0 0.03 (−4.92 ∼ 4.92)

Pituitary

0.61

0.57

0.68

0.65

0.61

0.61

0.61

0.62

−0.05 ∼ 0 0.06 (−20.00 ∼ 18.00)

IACs

0.59

0.50

0.52

0.50

0.55

0.44

0.40

0.50

−0.1 ∼ 0 0.09 (−4.92 ∼ 4.92)

Vestibul semises

0.61

0.60

0.63

0.59

0.61

0.60

0.53

0.60

−0.07 ∼ 0 0.03 (−11.67 ∼ 5.00)

  1. Abbreviations: NPC = Nasopharyngeal carcinoma; DSC = Dice similarity coefficient; OARs = Organs at risk; ET = Eustachian tube; IAC = Internal auditory canal; TMJ = Temporomandibular joint; GTVp = the gross target volume of primary tumor; GTVn = the gross tumor volume of lymph node; CTV = clinical target volume
  2. * Bone structures, volume for display only, not included in analysis of volume change trend
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Radiation Oncology

ISSN: 1748-717X

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