Fig. 5

Relation between sensitivity of DeltaDmax in CBW from S (scheduled) and A (adapted) plans to anatomical changes in the subsequent CT of the 91 delivered dose fractions. Blue circles indicate data points from plans optimized according to the goal list of method 1 and the red triangles according to method 2. In pairwise comparisons of data from the same dose fraction, adapted plans showed smaller DeltaDmax values than the respective scheduled plans (p < 0.0001, signed rank test)