Table 3 Univariate prognostic analysis
Variable | Cases No.(%) | Median OS (months) | 1-Year OS Rate(%) | 2-Year OS Rate(%) | 3-Year OS Rate(%) | χ2 | P | Median DFS (months) | 1-Year DFS Rate(%) | 2-Year DFS Rate(%) | 3-Year DFS Rate(%) | χ2 | P |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Age | 1.526 | 0.217 | 0.002 | 0.965 | |||||||||
≤ 76 years | 29 | 30 | 74.0 | 69.0 | 40.6 | 11 | 49.5 | 28.9 | 14.5 | ||||
> 76 years | 55 | 25 | 82.3 | 51.3 | 22.5 | 17 | 63.5 | 33.5 | 9.8 | ||||
Sex | 0.004 | 0.951 | 0.814 | 0.367 | |||||||||
Male | 67 | 27 | 80.7 | 57.7 | 25.3 | 15 | 52.8 | 30.8 | 9.2 | ||||
Female | 17 | 28 | 88.2 | 56.6 | 45.3 | 22 | 81.4 | 35.5 | 23.7 | ||||
Tumor Length | 0.318 | 0.573 | 0.340 | 0.560 | |||||||||
≤ 6 cm | 63 | 28 | 79.5 | 56.4 | 33.4 | 18 | 61.4 | 29.6 | 12.7 | ||||
> 6 cm | 21 | 27 | 90.0 | 60.0 | 15.2 | 16 | 50.4 | 39.2 | 8.2 | ||||
Tumor Location | 12.189 | 0.002 | 7.199 | 0.027 | |||||||||
Upper | 12 | 38 | 83.3 | 71.4 | 57.1 | 23 | 75.0 | 38.1 | 9.5 | ||||
Middle | 30 | 32 | 92.9 | 76.4 | 38.2 | 22 | 75.5 | 46.2 | 20.5 | ||||
Lower | 42 | 21 | 73.6 | 38.1 | 12.8 | 11 | 40.5 | 19.9 | 5.3 | ||||
Tumor Stage | 0.957 | 0.328 | 0.026 | 0.872 | |||||||||
Stage II | 50 | 28 | 84.9 | 61.2 | 31.6 | 16 | 59.6 | 28.2 | 14.8 | ||||
Stage III | 34 | 27 | 78.2 | 52.1 | 24.8 | 21 | 57.0 | 36.6 | 8.1 | ||||
KPS Score | 0.821 | 0.093 | 3.055 | 0.080 | |||||||||
70 | 34 | 24 | 75.3 | 46.8 | 21.2 | 14 | 54.0 | 25.4 | 4.9 | ||||
80–90 | 50 | 29 | 86.8 | 65.2 | 34.3 | 21 | 61.4 | 36.5 | 16.6 | ||||
Diabetes | 2.915 | 0.088 | 1.3 | 0.254 | |||||||||
No | 76 | 27 | 81.6 | 54.6 | 23.6 | 17 | 58.1 | 28.6 | 9.1 | ||||
Yes | 8 | 41 | 87.5 | 87.5 | 87.5 | 29 | 62.5 | 62.5 | 31.3 | ||||
Smoking | 0.022 | 0.881 | |||||||||||
No | 40 | 28 | 84.0 | 53.7 | 38.4 | 21 | 71.1 | 37.8 | 18.9 | 2.099 | 0.147 | ||
Yes | 44 | 27 | 80.3 | 59.9 | 24.0 | 12 | 46.9 | 26.1 | 7.8 | ||||
Hypertension | 0.123 | 0.726 | 0.001 | 0.980 | |||||||||
No | 40 | 24 | 76.9 | 49.8 | 21.1 | 18 | 58.5 | 28.1 | 9.4 | ||||
Yes | 44 | 28 | 86.1 | 63 | 34.1 | 16 | 58.3 | 34.5 | 13.2 | ||||
Underlying Lung Disease | 3.541 | 0.060 | 0.090 | 0.764 | |||||||||
No | 31 | 22 | 86.2 | 47.7 | 7.9 | 20 | 69.6 | 29.7 | 5.9 | ||||
Yes | 53 | 29 | 80.0 | 62.8 | 39.5 | 14 | 52.7 | 32.7 | 14 | ||||
Hyperthermia | 0.119 | 0.730 | 0.002 | 0.964 | |||||||||
No | 42 | 27 | 82.8 | 58.6 | 26.3 | 13 | 51.7 | 34.7 | 14.7 | ||||
Yes | 42 | 32 | 81.8 | 56.1 | 32.0 | 19 | 66.1 | 25.4 | 8.5 | ||||
Radiotherapy dose | 7.418 | 0.006 | 1.908 | 0.167 | |||||||||
≤ 60 Gy | 45 | 25 | 72.9 | 54.2 | 10.8 | 16 | 57.2 | 27.4 | 3.4 | ||||
> 60 Gy | 39 | 32 | 92.0 | 60.9 | 49.2 | 18 | 60.1 | 36.6 | 21.3 | ||||
Leukopenia | 0.113 | 0.737 | 0.028 | 0.867 | |||||||||
< Grade 2 | 64 | 28 | 83.1 | 57.8 | 25.3 | 19 | 59.9 | 34.8 | 9.2 | ||||
≥Grade 2 | 20 | 27 | 80.0 | 56.0 | 36.3 | 13 | 55.0 | 25.0 | 15.0 | ||||
Thrombocytopenia | 1.429 | 0.232 | 1.903 | 0.168 | |||||||||
< Grade 2 | 78 | 28 | 82.0 | 58.3 | 31.4 | 17 | 60.4 | 33.1 | 12.9 | ||||
≥Grade 2 | 6 | 15 | 83.3 | 41.7 | 20.8 | 7 | 33.3 | 16.7 | 0 | ||||
Anemia | 3.717 | 0.054 | 3.102 | 0.078 | |||||||||
< Grade 2 | 73 | 29 | 85.4 | 60.4 | 31.3 | 19 | 0.611 | 0.335 | 13.8 | ||||
≥Grade 2 | 11 | 18 | 60.6 | 36.4 | 12.1 | 12 | 41.6 | 20.8 | 0 | ||||
Hypoalbuminemia | 9.761 | 0.002 | 18.144 | < 0.001 | |||||||||
< Grade 2 | 72 | 29 | 86.4 | 63.2 | 31.0 | 21 | 65.9 | 36 | 13.9 | ||||
≥Grade 2 | 12 | 14 | 58.3 | 16.2 | 16.2 | 7 | 16.7 | 8.3 | 0 | ||||
Remission Status | 0.023 | 0.880 | 0.314 | 0.575 | |||||||||
No | 23 | 27 | 76.5 | 53.3 | 26.6 | 11 | 41.4 | 36.3 | 18.1 | ||||
Yes | 61 | 28 | 84.2 | 59.0 | 29.4 | 19 | 65.1 | 31.0 | 9.9 |