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This study aimed to evaluate the impact of pelvic radiation therapy (RT) on the occurrence of severe radiation-induced lymphopenia (SRIL) and identify its clinical and dosimetric predictors using voxel-wise an...
Breast cancer patients may use a bolus to increase the dose to skin in radiotherapy after radical mastectomy. The 3D printed bolus (3DPB) specifically customized based on individual conditions offers better co...
Stereotactic body radiotherapy (SBRT) for localized prostate cancer offers non-inferior oncological outcomes and toxicity profiles compared to conventionally or moderately hypofractioned radiotherapy regimens,...
The treatment of large arteriovenous malformations (AVMs), in particular those unruptured, remains a topic of debate. Stereotactic radiosurgery has favorable outcomes for small to medium-sized AVMs. However, f...
The wide adoption of intensity-modulated radiotherapy (RT) renders an extended neck position unnecessary. In this study, the appropriate craniocaudal border of the retropharyngeal lymph node (RPLN) was assesse...
Tumour-stroma ratio (TSR) is the proportion of tumour cells relative to surrounding stroma. This study aimed to investigate the prognostic impact of TSR, and to construct a prognostic nomogram in patients with...
Outcomes in glioblastoma are improved by surgical resection and adjuvant radiation (RT). In primary GBM (pGBM), large clinical target volume (CTV) margins typically cover occult invasion. In recurrent GBM (rGB...
Carbon ion radiotherapy (CIRT), a type of particle therapy, is at the forefront of clinical oncology treatments due to its superior physical properties and biological performance. Although CIRT has demonstrate...
This study aims to develop and validate a novel whole-body intensity-modulated proton therapy (IMPT) approach for total marrow/lymphatic irradiation (TMI/TMLI) and compare its efficacy to helical tomotherapy (...
The pituitary gland is an infrequent site for metastasis, encompassing approximately 0.4% of all intracranial metastatic lesions. The prognosis of pituitary metastasis (PM) remains dismal despite considerable ...
The use of prophylactic cranial irradiation (PCI) in early stage small cell lung cancer (SCLC) patients post-surgery remains controversial. This meta-analysis aimed to evaluate the efficacy of PCI in resected ...
Breast cancer-related lymphedema (BCRL) is a debilitating condition that affects a significant proportion of breast cancer survivors, profoundly impacting their quality of life. While many studies have investi...
Accurate pre-treatment dose prediction is essential for efficient radiotherapy planning. Although deep learning models have advanced automated dose distribution, comprehensive multi-tumor analyses remain scarc...
Primary small cell carcinoma of the esophagus (SCCE) is an aggressive carcinoma with a rare incidence. Most patients were diagnosed with stage III-IV and have a poor prognosis. The poor therapeutic outcomes of...
Radiotherapy (RT) is one of the four pillars of cancer treatment. Plesiotherapy, or contact brachytherapy, involves irradiating a tumor by placing small radioactive sources directly on the skin’s surface above...
Radiotherapy treatment planning traditionally involves complex and time-consuming processes, often relying on trial-and-error methods. The emergence of artificial intelligence, particularly Large Language Mode...
This study aimed to assess the clinical utility of deep hyperthermia in elderly patients with esophageal cancer(EC) who underwent intensity-modulated radiotherapy(IMRT).
The Acuros XB dose calculation algorithm implements advanced modelling of lateral electron transport, making dose distributions sensitive to density changes between source and subsequent CT. The aim of this st...
Vertebral compression fracture (VCF) is a potential serious complication of spinal stereotactic body radiotherapy (SBRT). Previously we noted a correlation between advanced Spinal Instability Neoplastic Score ...
Limited data exist on the effectiveness of concurrent chemoradiotherapy (CRT) using intensity-modulated radiation therapy (IMRT) after radical surgery in patients with node-positive early-stage cervical cancer...
Non-small cell lung cancer (NSCLC) patients receiving third-generation EGFR TKIs with thoracic radiotherapy (TRT) significantly prolong survival and also increase the incidence of radiation pneumonitis (RP). T...
The standard of care for locally advanced esophageal cancer includes perioperative chemotherapy or neo-adjuvant chemo-radiotherapy (CRT), followed by surgery. At our institution, a modified neo-adjuvant regime...
Adaptive treatment planning can be made in radiotherapy of head and neck cancer patients for reasons such as changes in tumor volume or weight loss. This study aims to find the role of treatment planning image...
The objective of this project was to develop and evaluate a comprehensive clinical quality assurance system for radiation oncology, and assess the system using definitive radiation therapy for prostate cancer ...
To quantify morphological and dosimetric variations in nasopharyngeal carcinoma (NPC) radiotherapy via autosegmented fan-beam computed tomography (FBCT) and to inform decision-making regarding appropriate obje...
The original article was published in Radiation Oncology 2025 20:16
In modern proton radiotherapy facilities with pencil beam scanning technology, the lowest energy of a proton beam typically ranges between 60 and 100 MeV, corresponding to a proton range in water of 3.1–7.5 cm...
Cardiotoxicity is a concern, especially in left breast cancer (BC) radiotherapy (RT), and accurate dosimetry is essential for minimizing cardiac exposure. This study evaluated the radiation exposure of cardiac...
Radiotherapy is a crucial treatment modality for head and neck tumors. Precise patient positioning is vital for ensuring the reproducibility and accuracy of the treatment. Clinically, thermoplastic head and ne...
Advancements in nodal staging for head and neck squamous cell carcinoma (HNSCC) have prompted radiotherapy de-escalation trials to reduce irradiation of electively treated neck regions, with the goal of improv...
Head-and-neck squamous cell carcinomas (HNSCC) exhibit significant variations in incidence and outcomes across age groups. There is conflicting data on the oncological outcomes of younger HNSCC patients ≤ 45 y...
Leptomeningeal disease (LMD) is a fatal complication of cancer linked to poor survival rates and limited treatment options. While photon involved-field radiotherapy is the standard of care for local palliation...
To evaluate the incidence of symptomatic radiation pneumonitis (RP) in lung cancer patients receiving immunotherapy and radiotherapy.
Delineating the internal gross tumor volume (IGTV) is crucial for the treatment of non-small cell lung cancer (NSCLC). Deep learning (DL) enables the automation of this process; however, current studies focus ...
Esophageal cancer is one of the most common malignant tumors, with China accounting for 50% of the world’s total incidence. Concurrent chemoradiotherapy (cCRT) with platin-based dual-drug regimen is the standa...
Adaptive radiation therapy (ART) allows real-time treatment plan adjustment based on daily anatomical changes but involves a time-consuming workflow. Surface-guided radiation therapy (SGRT) provides precise pa...
This study aimed to identify dosiomic features that have a significant impact on biochemical failure (BCF) following low-dose rate (LDR) brachytherapy treatment using Iodine-125 seeds for prostate cancer and t...
This study sought to examine the current state and explore the key areas and emerging trends in radiation dermatitis prevention and management through bibliometric analysis, with the goal of providing valuable...
This study aims to explore the most influential countries/regions, institutions, journals, authors, keywords, and trends in the study of the mechanism and treatments of radiation dermatitis (RD) from 2003 to 2...
Although partial breast irradiation (PBI) is accepted as an effective and cosmesis-preserving technique for low-risk early-stage breast cancer following standard lumpectomy, data supporting PBI following oncop...
This study aimed to determine the clinical impact of radiation response on survival in patients with medulloblastoma (MB) and to explore the predictive factor of radiation response.
In radiotherapy, inadequate management of organ motion in liver cancer may lead to inadequate delineation accuracy, resulting in the underdosage of target tissues and overdosage of surrounding normal tissues. ...
Brain metastases are common complications in patients with cancer and significantly affect prognosis and treatment strategies. The accurate segmentation of brain metastases is crucial for effective radiation t...
Mathematical modeling has long been a cornerstone of radiotherapy for cancer, guiding treatment prescription, planning, and delivery through versatile applications. As we enter the era of medical big data, whe...
This study reports the single-institution clinical experience of multifield pencil beam scanning (PBS) intensity-modulated proton therapy (IMPT) and dosimetric comparison to proton arc for uveal melanoma (UM) ...
This study aimed to identify key risk factors in locally advanced cervical cancer (LACC) patients receiving radical radiotherapy and to evaluate the prognostic significance of MRI-determined tumor volume regre...
There is a substantial body of literature addressing the prevention, acute management, and follow-up care of radiation induced dermatitis (RID). The quality and application of this evidence, however, is incons...
To evaluate the impact of smoking on acute and chronic toxicity in early breast cancer patients treated with hypofractionated intensity-modulated radiation therapy (IMRT) and a brachytherapy boost following br...
To explore the feasibility and advantages of the visualized thermosensitive color-changing personalized bolus in post-mastectomy radiotherapy (PMRT).
Patients with synchronous metastatic nasopharyngeal carcinoma (smNPC) exhibit significant heterogeneity, and clinical prognostic models suitable for this cohort remain limited. We aimed to develop a prognostic...
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